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KIF4A Antibody

SKU : BHA10558344

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA266335
Alternative Names	chromokinesin; chromosome-associated kinesin KIF4A; KIF4; KIF4-G1; kinesin family member 4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.Villard L., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.Oh S.J., Biochim. Biophys. Acta 1493:219-224(2000).Rentsch A., Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human KIF4A.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Villard L., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases. Oh S.J., Biochim. Biophys. Acta 1493:219-224(2000). Rentsch A., Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total KIF4A protein.
Subcellular Location	Nucleus matrix, Cytoplasm, cytoskeleton, spindle, Midbody, Chromosome

Uniprot	O95239
Database Links	HGNC:13339 OMIM:300521 KEGG:hsa:24137 STRING:9606.ENSP00000363524 UniGene:Hs.648326
Function	Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
Protein Families	TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Chromokinesin subfamily
Tissue Specificity	Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558344	CSB-PA266335	100ul	$297		Add to Cart

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