Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1; Potassium channel subfamily K member 1;
Categories
Primary Antibodies
Clonality
polyclonal
Description
Weakly inward rectifying potassium channel.Lesage F., EMBO J. 15:1004-1011(1996).Goldstein S.A.N., J. Mol. Med. 76:13-20(1998).Orias M., Am. J. Physiol. 273:F663-F666(1997)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human KCNK1.
Raised In
Rabbit
Reactivity
Human, Rat
Regulatory
RUO
Relevance
Weakly inward rectifying potassium channel.
Lesage F., EMBO J. 15:1004-1011(1996). Goldstein S.A.N., J. Mol. Med. 76:13-20(1998). Orias M., Am. J. Physiol. 273:F663-F666(1997)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total KCNK1 protein.
Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues
Protein Families
Two pore domain potassium channel (TC 1.A.1.8) family
Tissue Specificity
Detected in bronchial epithelial cells (PubMed:21964404). Detected in heart left atrium and left ventricle (PubMed:17478540). Detected in cardiac myocytes (at protein level) (PubMed:21653227). Widely expressed with high levels in heart, brain and kidney,
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.