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Home / Primary Antibodies

KCNJ4 Antibody

SKU : BHA10558864

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA971432
Alternative Names	Hippocampal inward rectifier; HIRK2; HRK1; Inward rectifier K channel Kir2.3; Inward rectifier potassium channel 4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium By similarity.Perier F., Proc. Natl. Acad. Sci. U.S.A. 91:6240-6244(1994).Tang W., FEBS Lett. 348:239-243(1994).Makhina E.N., J. Biol. Chem. 269:20468-20474(1994).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human KCNJ4.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium By similarity. Perier F., Proc. Natl. Acad. Sci. U.S.A. 91:6240-6244(1994). Tang W., FEBS Lett. 348:239-243(1994). Makhina E.N., J. Biol. Chem. 269:20468-20474(1994).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total KCNJ4 protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein, Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cytoplasmic vesicle membrane

Uniprot	P48050
Database Links	HGNC:6265 OMIM:600504 KEGG:hsa:3761 STRING:9606.ENSP00000306497 UniGene:Hs.32505
Function	Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
Protein Families	Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ4 subfamily
Tissue Specificity	Heart, skeletal muscle, and several different brain regions including the hippocampus.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558864	CSB-PA971432	100ul	$297		Add to Cart

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