Human intelectin-1 (ITLN-1) is a novel identified galactose binding lectin that is usually expressed in the heart, small intestine, and colon. In normal tissues, human intelectin-1 was mainly secreted from gastrointestinal goblet cells along with mucus into the intestinal lumen, and it was also expressed, to a lesser extent, in mesothelial cells and urinary epithelial cells. It is overexpressed in human malignant pleural mesothelioma (MPM). In contrast, sarcomatoid-type MPMs, biphasic MPMs, and poorly differentiated MPMs are rarely positive for intelectin-1, and it is not expressed in other cancers, except in mucus-producing adenocarcinoma.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A portion of amino acids 16-141 from the human protein was used as the immunogen for the ITLN1 antibody.
Isotype
Mouse IgG1, kappa
Species Reactivity
Human
Note
Optimal dilution of the ITLN1 antibody should be determined by the researcher.
Uniprot
Q8WWA0
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the ITLN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Applications
IHC-P
Description
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT