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Home / Antibodies

ITGAX Antibody

SKU : BHA10557550

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA091944
Alternative Names	SLEB6; ITGAX;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Integrin a-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009)
Host	Rabbit
Immunogen	Peptide sequence around aa.1155~1159(Q-T-P-S-P)derived from Human CD11c.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Integrin a-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.J. Proteome Res. 8:651-661(2009)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total CD11c protein.
Subcellular Location	Membrane, Single-pass type I membrane protein

Uniprot	P20702
Database Links	HGNC:6152 OMIM:151510 KEGG:hsa:3687 STRING:9606.ENSP00000268296 UniGene:Hs.248472
Function	Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Pathway	Regulation of actin cytoskeleton Complement and coagulation cascades
Protein Families	Integrin alpha chain family
Tissue Specificity	Predominantly expressed in monocytes and granulocytes.

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557550	CSB-PA091944	100ul	$297		Add to Cart

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