Integrator complex subunit 6 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 135-167 from the human protein was used as the immunogen for the INTS6 antibody.
Isotype
Ig
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
Q9UL03
Gene Id
26512
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
Aliquot the INTS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.