Recognizes a protein of 20-25kDa, identified as human interferon. This mAb is specific to human IFNg and recognizes both recombinant and native human IFNg. It does not neutralize the activity of IFNg. T lymphocytes and NK cells mainly produce IFN-. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFNa/b (type I interferon).
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
Purified recombinant human IFNG was used as the immunogen for the Interferon gamma antibody.
Isotype
Mouse IgG1, kappa
Species Reactivity
Human
Note
Optimal dilution of the Interferon gamma antibody should be determined by the researcher.
Uniprot
P01579
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the Interferon gamma antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).