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Home / Antibodies

Integrin alpha V Antibody / ITGAV / Vitronectin Receptor (V8282SAF)

SKU : BHA17127369

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NSJ Bioreagents

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Mfr.No.	V8282SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin Receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. Reacts with Integrin Alpha V Beta 3. 23C6 may be useful for bone resorption modulation, osteoclast identification, receptor purification, malignant melanoma identification and treatment.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Osteoclasts from osteoclastomas were used as the immunogen for the Vitronectin Receptor antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P06756

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Vitronectin Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA-free format for coating)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/vitronectin-receptor-antibody-23c6-v8282" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127369	V8282SAF-100UG	100 ug	$499		Add to Cart

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