B cell growth factor 1; B cell stimulatory factor 1; B-cell stimulatory factor 1; BCGF-1; BCGF1
Categories
Primary Antibodies
Clonality
polyclonal
Description
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.Yokota T., Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986).Arai N., J. Immunol. 142:274-282(1989).Klein S.C., Immunogenetics 41:57-57(1995).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human IL4.
Involvement In Disease
Ischemic stroke (ISCHSTR)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Yokota T., Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986). Arai N., J. Immunol. 142:274-282(1989). Klein S.C., Immunogenetics 41:57-57(1995).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total IL4 protein.