Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.Dunham I., Genome Biol. 5:R84.1-R84.11(2004).Venter J.C., Submitted (JUL-2005).Henzel W.J., Protein Sci. 13:2819-2824(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human IL17RA.
Involvement In Disease
Immunodeficiency 51 (IMD51)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
Dunham I., Genome Biol. 5:R84.1-R84.11(2004). Venter J.C., Submitted (JUL-2005). Henzel W.J., Protein Sci. 13:2819-2824(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total IL17RAprotein.
Subcellular Location
Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Secreted