The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 50-77 from the human protein was used as the immunogen for this IL-2 antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
Titration of the IL-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P60568
Format
Ascites
Purity
Ascites
Storage
Aliquot the IL-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.