I kappa B kinase beta, also known as IKKb or NFKBIKB, is a protein that in humans is encoded by the IKBKB gene.<a href=../search_result.php?search_txt=ikba>IkBa</a>binds and inhibits NF-kB in the cytoplasm. Activated IKKb phosphorylates IkBa, which frees<a href=../search_result.php?search_txt=nfkb>NFkB</a>to translocate to the nucleus. It is found that mutations in IKKb had a more pronounced effect upon NFKB activation than did comparable mutations in<a href=../search_result.php?search_txt=ikk%20alpha>IKKa</a>.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 398-756) was used as the immunogen for this IKKb antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Gene Id
3551
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the IKKb antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.