This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the pateal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alteatively spliced transcript variants encoding different isoforms have been found for this gene.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 39-68 from the human protein was used as the immunogen for this IGF2 antibody.
Isotype
Mouse IgM
Species Reactivity
Human
Note
Titration of the IGF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P01344
Format
Ascites
Purity
Ascites
Storage
Aliquot the IGF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.