This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 39-68 from the human protein was used as the immunogen for this IGF2 antibody.
Isotype
IgM
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
P01344
Clone No
519CT14.3.6
Format
Ascites
Purification
Ascites
Storage
Aliquot the IGF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.