May play a key role in the development of multiple organ systems and particularly in cardiac development By similarity.Togawa K.,J. Cell. Physiol. 183:129-139(2000).Yang T.,Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.Nagase T.,DNA Res. 6:63-70(1999).
Host
Rabbit
Immunogen
Synthesized non-phosphopeptide derived from Human ICK around the phosphorylation site of tyrosine 159 (T-D-Y(p)-V-S).
Involvement In Disease
Endocrine-cerebroosteodysplasia (ECO)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
May play a key role in the development of multiple organ systems and particularly in cardiac development By similarity.
Togawa K.,J. Cell. Physiol. 183:129-139(2000). Yang T.,Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases. Nagase T.,DNA Res. 6:63-70(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ICK protein.
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Tissue Specificity
Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.