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Home / Antibodies

hUPF2 Antibody / RENT2 (RQ6694)

SKU : BHA17119108

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NSJ Bioreagents

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Mfr.No.	RQ6694
Cellular Localization	Cytoplasmic
Clonality	Polyclonal (rabbit origin)
Description	Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids K200-H651) was used as the immunogen for the hUPF2 antibody.
Isotype	Rabbit IgG
Reactivity	Human
Recombinant	No

Uniprot	Q9HAU5

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the hUPF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, FACS, IF, Direct ELISA
Dilution	Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Immunofluorescence: 5ug/ml,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119108	RQ6694	100ug	$419		Add to Cart

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