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HTR3A Antibody

SKU : BHA10558304

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA786914
Alternative Names	5-HT-3; 5-HT3R; 5-hydroxytryptamine 3 receptor; 5HT3R; HTR3
Categories	Primary Antibodies
Clonality	polyclonal
Description	This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.Miyake A., Mol. Pharmacol. 48:407-416(1995).Belelli D., Mol. Pharmacol. 48:1054-1062(1995).Yamada K., Biol. Psychiatry 60:192-201(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human 5-HT-3A.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. Miyake A., Mol. Pharmacol. 48:407-416(1995). Belelli D., Mol. Pharmacol. 48:1054-1062(1995). Yamada K., Biol. Psychiatry 60:192-201(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total 5-HT-3A protein.
Subcellular Location	Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein

Uniprot	P46098
Database Links	HGNC:5297 OMIM:182139 KEGG:hsa:3359 UniGene:Hs.413899
Function	This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Protein Families	Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3A sub-subfamily
Tissue Specificity	Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558304	CSB-PA786914	100ul	$297		Add to Cart

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