Heat shock 60KD protein is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. It can downregulate adaptive immune responses by upregulating Tregs innately through<a href=../search_result.php?search_txt=tlr2>TLR2</a>signaling.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of rat HSP60 (YDAMLGDFVNMVEK) was used as the immunogen for this HSP60 antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Uniprot
P63039
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
The lyophilized HSP60 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
Applications
WB, IHC-P, ICC
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml