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Home / Primary Antibodies

HSF1 (Ab-142) Antibody

SKU : BHA10557668

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA268961
Alternative Names	Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1; HSTF 1; HSTF1
Categories	Primary Antibodies
Clonality	polyclonal
Description	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.Rabindran S.K., Proc. Natl. Acad. Sci. U.S.A. 88:6906-6910(1991).Ota T., Nat. Genet. 36:40-45(2004).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human HSF1 around the phosphorylation site of threonine 142 (L-L-T(p)-D-V).
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. Rabindran S.K., Proc. Natl. Acad. Sci. U.S.A. 88:6906-6910(1991). Ota T., Nat. Genet. 36:40-45(2004). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total HSF1 protein.
Subcellular Location	Nucleus, Cytoplasm, Nucleus, nucleoplasm, Cytoplasm, perinuclear region, Cytoplasm, cytoskeleton, spindle pole, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore

Uniprot	Q00613
Database Links	HGNC:5224 OMIM:140580 KEGG:hsa:3297 STRING:9606.ENSP00000431512 UniGene:Hs.530227
Function	Function as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults' damage
Protein Families	HSF family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557668	CSB-PA268961	100ul	$297		Add to Cart

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