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Home / Antibodies

HLA-DPB1 Antibody (MHC II) (F54283)

SKU : BHA17102756

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NSJ Bioreagents

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Mfr.No.	F54283, F54283-0.08ML, F54283-0.4ML
Clonality	Polyclonal
Description	HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 77-105 from the human protein were used as the immunogen for the HLA-DPB1 antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cell surface

Uniprot	P04440

Format	Purified
Purification	Antigen affinity purified
Storage	Aliquot the HLA-DPB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P, FACS
Dilution	Weste blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25,Flow cytometry: 1:25 (1x10e6 cells)

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102756-1	F54283-0.08ML	0.08ml	$165		Add to Cart
BHA17102756-2	F54283-0.4ML	0.4ml	$379		Add to Cart

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