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Home / Primary Antibodies

HLA-DOB Antibody

SKU : BHA10558445

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA270928
Alternative Names	HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.Tonnelle C., EMBO J. 4:2839-2847(1985).Jonsson A.-K., Immunogenetics 29:411-413(1989).Beck S., J. Mol. Biol. 228:433-441(1992).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human HLA-DOB.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM. Tonnelle C., EMBO J. 4:2839-2847(1985). Jonsson A.-K., Immunogenetics 29:411-413(1989). Beck S., J. Mol. Biol. 228:433-441(1992).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total HLA-DOB protein.
Subcellular Location	Endosome membrane, Single-pass type I membrane protein, Lysosome membrane, Single-pass type I membrane protein

Uniprot	P13765
Database Links	HGNC:4937 OMIM:142920 KEGG:hsa:3112 STRING:9606.ENSP00000390020 UniGene:Hs.1802
Function	Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Pathway	Antigen processing and presentation Hematopoietic cell lineage Th1 and Th2 cell differentiation Th17 cell differentiation
Protein Families	MHC class II family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558445	CSB-PA270928	100ul	$297		Add to Cart

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