Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.
Isotype
Mouse IgG2a, kappa
Species Reactivity
Human
Note
Optimal dilution of the HLA-ABC antibody should be determined by the researcher.
Uniprot
P01889; P30443; P30499
Format
Purified
Purity
Protein A/G affinity
Storage
Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.