Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.Doenecke D., J. Mol. Biol. 187:461-464(1986).Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).Dunham I., Nature 402:489-495(1999).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human Histone 1F0.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Doenecke D., J. Mol. Biol. 187:461-464(1986). Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004). Dunham I., Nature 402:489-495(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Histone 1F0 protein.
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Protein Families
Histone H1/H5 family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.