ARNT (aryl hydrocarbon receptor nuclear translocator) encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of ARNT with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants
Clonality
Monoclonal
Formulation
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Host
Mouse
Immunogen
Recombinant Protein
Isotype
Mouse IgG1
Reactivity
Mouse
Gene Id
405
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer
PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide