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Home / Primary Antibodies

HGAL Antibody / GCSAM / GCET2 (V8782)

SKU : BHA17119337

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NSJ Bioreagents

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Mfr.No.	V8782, V8782-20UG, V8782-100UG
Clonality	Monoclonal (mouse origin)
Description	Germinal center-associated signaling and motility protein / GCSAM, also called GCET2 and HGAL or hGAL, contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 1-200 was used as the immunogen for the HGAL antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the HGAL antibody should be determined by the researcher.

Uniprot	Q8N6F7

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the HGAL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17119337-1	V8782-20UG	20ug	$219		Add to Cart
BHA17119337-2	V8782-100UG	100ug	$499		Add to Cart

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