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Home / Antibodies

HEY2 Antibody

SKU : BHA10558046

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA993153
Alternative Names	Hairy/enhancer-of-split related with YRPW motif protein 2; Cardiovascular helix-loop-helix factor 1; hCHF1; Hairy and enhancer of split-related protein 2; HESR-2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.Chin M.T., J. Biol. Chem. 275:6381-6387(2000).Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000).Iso T., Mol. Cell. Biol. 21:6071-6079(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human HEY2.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Chin M.T., J. Biol. Chem. 275:6381-6387(2000). Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000). Iso T., Mol. Cell. Biol. 21:6071-6079(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total HEY2 protein.
Subcellular Location	Nucleus

Uniprot	Q9UBP5
Database Links	HGNC:4881 OMIM:604674 KEGG:hsa:23493 STRING:9606.ENSP00000357348 UniGene:Hs.144287
Function	Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Protein Families	HEY family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558046	CSB-PA993153	100ul	$297		Add to Cart

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