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Home / Primary Antibodies

HEXIM1 Antibody

SKU : BHA10559252

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA556810
Alternative Names	Protein HEXIM1; Hexamethylene bis-acetamide-inducible protein 1; Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; Menage a quatre protein 1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.Kusuhara M., Biomed. Res. 20:273-279(1999).Wittmann B.M., Cancer Res. 63:5151-5158(2003).Ouchida R., Genes Cells 8:95-107(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human HES7.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Kusuhara M., Biomed. Res. 20:273-279(1999). Wittmann B.M., Cancer Res. 63:5151-5158(2003). Ouchida R., Genes Cells 8:95-107(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total HES7 protein.
Subcellular Location	Nucleus, Cytoplasm

Uniprot	O94992
Database Links	HGNC:24953 OMIM:607328 KEGG:hsa:10614 STRING:9606.ENSP00000328773 UniGene:Hs.586945
Function	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor
Protein Families	HEXIM family
Tissue Specificity	Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559252	CSB-PA556810	100ul	$297		Add to Cart

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