This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A recombinant human HER2 protein fragment within amino acids 311-462 was used as the immunogen for the HER2 antibody.
Isotype
Mouse IgG
Species Reactivity
Human
Note
Optimal dilution of the antibody should be determined by the researcher.
Uniprot
P04626
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the HER2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).