Mouse Anti-Rat HCN4 Monoclonal IgG1

Mfr.No.	SMC-320, SMC-320D, SMC-320D-A390, SMC-320D-A488, SMC-320D-A594, SMC-320D-ALP, SMC-320D-APC, SMC-320D-BI, SMC-320D-FITC, SMC-320D-HRP, SMC-320D-PCP, SMC-320D-RPE, SMC-320S
Immunogen Species	Rat
Alternative Names	Hyperpolarization activated cyclic nucleotide gated potassium channel 4 Antibody, HCN 4 Antibody, Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 4 Antibody
Categories	Antibodies
Cellular Localization	Membrane
Certificate Of Analysis	1 ug/ml of SMC-320 was sufficient for detection of HCN4 in 10 ug of COS cell lysate transiently transfected with HCN4 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Rat HCN4 Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Fusion protein amino acids 1-019-1198 (c-terminus) of rat HCN4, Rattus Norvegicus (Rat)
Immunogen Region	Fusion protein amino acids 1019-1198 (c-terminus) of rat HCN4
Isotype	IgG1
Launch Date	2009/07/06
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human, Rabbit
Recombinant	FALSE
Regulatory	RUO
Species	Rattus Norvegicus (Rat)
Species Reactivity Medium	Mouse, Rat, Rabbit, Human

Swissprot	Q9JKA7
Accession Number	NP_067690.1
Gene Id	59266
Target	HCN4
Clone No	N114/10
Research Area	cardiovascular System, Ion Channels, Cyclic Nucleotide-Gated Ion Channels, Heart, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Hyperpolarization-activated cation channels of the HCN gene family contribute to spontaneous rhythmic activity in both the heart and brain (1).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~130kDa. No cross-reactivity against other HCNs.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, IHC, WB, ICC/IF, FACS
Description	WB ; IHC ; ICC ; IF ; AM
Dilution	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Zong X., et al. (2005) J Biol Chem. 280(40): 34224-34232

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11902823-1	SMC-320D	Unconjugated	100 ug	$330	Add to Cart
BHA11902823-2	SMC-320D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11902823-3	SMC-320D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11902823-4	SMC-320D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11902823-5	SMC-320D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11902823-6	SMC-320D-APC	APC	100 ug	$382	Add to Cart
BHA11902823-7	SMC-320D-BI	Biotin	100 ug	$378	Add to Cart
BHA11902823-8	SMC-320D-FITC	FITC	100 ug	$374	Add to Cart
BHA11902823-9	SMC-320D-HRP	HRP	100 ug	$370	Add to Cart
BHA11902823-10	SMC-320D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11902823-11	SMC-320D-RPE	RPE	100 ug	$380	Add to Cart
BHA11902823-12	SMC-320S	Unconjugated	12 ug	$44	Add to Cart

HCN4 Antibody, Clone N114/10 - SMC-320