Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.Muzny D.M., Nature 440:1194-1198(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human HCLS1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Kitamura D., Nucleic Acids Res. 17:9367-9379(1989). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Muzny D.M., Nature 440:1194-1198(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total HCLS1 protein.
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Tissue Specificity
Expressed only in tissues and cells of hematopoietic origin.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.