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Home / Antibodies

HAT1 Antibody

SKU : BHA10557740

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA928867
Alternative Names	Histone acetyltransferase 1; Histone acetyltransferase type B catalytic subunit; EC 2.3.1.48; HAT1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.Claudia J. Schroder-Adams, Bulletin of Canadian Petroleum Geology, Sep 1997; 45: 356 - 376. Pil-Hoon Park, Am J Physiol Gastrointest Liver Physiol, Dec 2005; 289: G1124 - G1136. Claudia J. Schroeder-Adams, Palaios, Aug 1998; 13: 361 - 375. L. J. Patric
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human HAT.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. Claudia J. Schroder-Adams, Bulletin of Canadian Petroleum Geology, Sep 1997; 45: 356 - 376. Pil-Hoon Park, Am J Physiol Gastrointest Liver Physiol, Dec 2005; 289: G1124 - G1136. Claudia J. Schroeder-Adams, Palaios, Aug 1998; 13: 361 - 375. L. J. Patric
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total HAT protein.
Subcellular Location	Isoform A: Nucleus matrix, SUBCELLULAR LOCATION: Isoform B: Cytoplasm, Nucleus, Nucleus matrix, Nucleus, nucleoplasm

Uniprot	O14929
Database Links	HGNC:4821 OMIM:603053 KEGG:hsa:8520 STRING:9606.ENSP00000264108 UniGene:Hs.632532
Function	Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
Protein Families	HAT1 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557740	CSB-PA928867	100ul	$297		Add to Cart

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