Heart- and neural crest derivatives-expressed protein 1; Extraembryonic tissues; heart; autonomic nervous system and neural crest derivatives-expressed protein 1; eHAND
Categories
Primary Antibodies
Clonality
polyclonal
Description
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) By similarity.Knoefler M., Gene 224:77-86(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human HAND1.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) By similarity.
Knoefler M., Gene 224:77-86(1998). The MGC Project Team, Genome Res. 14:2121-2127(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total HAND1 protein.
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Pathway
Signaling pathways regulating pluripotency of stem cells
Tissue Specificity
Heart.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.