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Home / Antibodies

GZMH Antibody

SKU : BHA10559414

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA966723
Alternative Names	Granzyme H [Precursor]; EC 3.4.21.-; Cytotoxic T-lymphocyte proteinase; Cathepsin G-like 2; CTSGL2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.Meier M., Biochemistry 29:4042-4049(1990).Haddad P., Int. Immunol. 3:57-66(1991).Klein J.L., Tissue Antigens 35:220-228(1990).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GRAH.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. Meier M., Biochemistry 29:4042-4049(1990). Haddad P., Int. Immunol. 3:57-66(1991). Klein J.L., Tissue Antigens 35:220-228(1990).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GRAH protein.
Subcellular Location	Cytoplasmic granule

Uniprot	P20718
Database Links	HGNC:4710 OMIM:116831 KEGG:hsa:2999 STRING:9606.ENSP00000216338 UniGene:Hs.348264
Function	Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.
Protein Families	Peptidase S1 family, Granzyme subfamily
Tissue Specificity	Constitutively expressed in NK cells.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559414	CSB-PA966723	100ul	$297		Add to Cart

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