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Home / Antibodies

GTF2H2 Antibody / BTF2 p44 / TFIIH (V9196)

SKU : BHA17119585

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NSJ Bioreagents

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Mfr.No.	V9196, V9196-20UG, V9196-100UG
Clonality	Monoclonal (mouse origin)
Description	Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and Mat1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant full-length human GTF2H2 protein was used as the immunogen for the BTF2 p44 antibody.
Isotype	Mouse IgG1
Species Reactivity	Human
Note	Optimal dilution of the BTF2 p44 antibody should be determined by the researcher.

Uniprot	Q13888

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the BTF2 p44 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	FACS, IF
Description	Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17119585-1	V9196-20UG	20ug	$219		Add to Cart
BHA17119585-2	V9196-100UG	100ug	$499		Add to Cart

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