Rabbit Anti-Human GRK2 (pTyr356) Polyclonal

Mfr.No.	SPC-922, SPC-922D, SPC-922D-A390, SPC-922D-A488, SPC-922D-A594, SPC-922D-BI, SPC-922D-FITC
Immunogen Species	Human
Alternative Names	ADRBK1 Antibody, Adrenergic beta receptor kinase 1 Antibody, ARBK1_HUMAN Antibody, BARK Antibody, BARK1 Antibody, Beta adrenergic receptor kinase 1 Antibody, Beta ARK 1 Antibody, G protein coupled receptor kinase 2 Antibody
Categories	Antibodies
Cellular Localization	Cytoplasm, Cell Membrane
Certificate Of Analysis	A 1:250 dilution of SPC-922 was sufficient for detection of GRK2 (pTyr356) in 10 ug of human colon cancer cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human GRK2 (pTyr356) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Tyr356 of human GRK2 (AA353-359), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Tyr356 of human GRK2 (AA353-359)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Expressed in peripheral blood leukocytes.

Swissprot	P25098
Accession Number	NP_001610
Gene Id	156
Target	GRK2 (pTyr356)
Research Area	Neurotransmission, Neurotransmitter Receptors, Cell Signaling, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Expressed in peripheral blood leukocytes.
Scientific Background	G protein-coupled receptor kinases (GRKs) belong to a class of enzymes that regulate signal transduction. At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of beta-adrenergic receptor kinase: GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 79.574 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11911412-1	SPC-922D	Unconjugated	100 ul	$331	Add to Cart
BHA11911412-2	SPC-922D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11911412-3	SPC-922D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11911412-4	SPC-922D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11911412-5	SPC-922D-BI	Biotin	100 ul	$380	Add to Cart
BHA11911412-6	SPC-922D-FITC	FITC	100 ul	$375	Add to Cart

GRK2 Antibody (pTyr356) - SPC-922