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Home / Antibodies

GRID2 Antibody

SKU : BHA10559407

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA269961
Alternative Names	GluR delta-2; GLURD2; glutamate receptor delta-2;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.Hu W., Genomics 47:143-145(1998).Sjoeblom T., Science 314:268-274(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GRID2.
Involvement In Disease	Spinocerebellar ataxia, autosomal recessive, 18 (SCAR18)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Hu W., Genomics 47:143-145(1998). Sjoeblom T., Science 314:268-274(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GRID2 protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein, Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein

Uniprot	O43424
Database Links	HGNC:4576 OMIM:602368 KEGG:hsa:2895 STRING:9606.ENSP00000282020 UniGene:Hs.162727
Function	Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex
Protein Families	Glutamate-gated ion channel (TC 1.A.10.1) family, GRID2 subfamily

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559407	CSB-PA269961	100ul	$297		Add to Cart

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