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Home / Primary Antibodies

Granzyme A Antibody (R30665)

SKU : BHA17104267

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Mfr.No.	R30665
Clonality	Polyclonal
Description	Granzyme A is a protein that in humans is encoded by the GZMA gene. Cytolytic T lymphocytes(CTL) and natural killer(NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are though to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. GZMA induces caspase-independent apoptosis in a characteristic manner, except it causes a distinctive form of DNA damage: single-stranded DNA nicking. A target of GZMA is the SET complex, including HMGB2 and ANP32A .
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human Granzyme A (DRKVCNDRNHYNFNPV) was used as the immunogen for this Granzyme A antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P12544

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Granzyme A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104267	R30665	100 ug	$419		Add to Cart

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