In addition to it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A recombinant human full-length protein was used as the immunogen for the Glucose 6-Phosphate Isomerase antibody.
Isotype
Mouse IgG2a, kappa
Species Reactivity
Human
Note
Optimal dilution of the antibody should be determined by the researcher.
Uniprot
P06744
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the Glucose 6-Phosphate Isomerase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).