ACHM4; GNATC; guanine nucleotide binding protein (G protein); alpha transducing activity 2; guanine nucleotide-binding protein G(t) alpha-2
Categories
Primary Antibodies
Clonality
polyclonal
Description
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.Lerea C.L., Neuron 3:367-376(1989).Kubo M., FEBS Lett. 291:245-248(1991).Morris A.T., Genomics 17:442-448(1993).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human GNAT2.
Involvement In Disease
Achromatopsia 4 (ACHM4)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Lerea C.L., Neuron 3:367-376(1989). Kubo M., FEBS Lett. 291:245-248(1991). Morris A.T., Genomics 17:442-448(1993).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total GNAT2 protein.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Protein Families
G-alpha family, G(i/o/t/z) subfamily
Tissue Specificity
Retinal rod outer segment.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.