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Home / Antibodies

Glycoprotein 2 Antibody / GP2 / ZAP75 (V3873SAF)

SKU : BHA17125694

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NSJ Bioreagents

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Mfr.No.	V3873SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the Glycoprotein 2 antibody.
Isotype	Mouse IgG2c, kappa
Species Reactivity	Human
Note	Optimal dilution of the Glycoprotein 2 antibody should be determined by the researcher.

Uniprot	P55259

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Glycoprotein 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, ELISA, IHC-P
Description	ELISA: 2-4ug/ml (order BSA/azide-free format),Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125694	V3873SAF-100UG	100 ug	$499		Add to Cart

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