Glutamate receptor 1 is a protein that in humans is encoded by the GLUR1 gene. mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. GLUR1/GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GLUR1-4) include flip and flop isoforms generated by alteative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 19-360) was used as the immunogen for this GLUR1 antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Gene Id
2890
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the GLUR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.