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Home / Primary Antibodies

GLUL Antibody

SKU : BHA10557628

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA824698
Alternative Names	GS; GLNS; PIG43; PIG59;
Categories	Primary Antibodies
Clonality	polyclonal
Description	This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner . Essential for proliferation of fetal skin fibroblasts. "Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase." Boksha I.S., Schonfeld H.J., Langen H. Biokhimiia 67:1012-1020(2002) "Glutamine synthetase is essential for proliferation of fetal skin fibroblasts." Vermeulen T., Goerg B., Vogl T. Arch. Biochem. Biophys. 478:96-102(2008)
Host	Rabbit
Immunogen	Peptide sequence around aa.365~369(G-D-E-P-F) derived from Human Glutamine Synthetase
Involvement In Disease	Congenital systemic glutamine deficiency (CSGD)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner . Essential for proliferation of fetal skin fibroblasts. "Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase." Boksha I.S., Schonfeld H.J., Langen H. Biokhimiia 67:1012-1020(2002) "Glutamine synthetase is essential for proliferation of fetal skin fibroblasts." Vermeulen T., Goerg B., Vogl T. Arch. Biochem. Biophys. 478:96-102(2008)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Glutamine Synthetase protein.
Subcellular Location	Cytoplasm, Mitochondrion

Uniprot	P15104
Database Links	HGNC:4341 OMIM:138290 KEGG:hsa:2752 STRING:9606.ENSP00000307900 UniGene:Hs.132016
Function	This enzyme has 2 functions
Pathway	Necroptosis Glutamatergic synapse
Protein Families	Glutamine synthetase family

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557628	CSB-PA824698	100ul	$297		Add to Cart

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