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Home / Primary Antibodies / Monoclonal Antibodies

GluA1/GluR1 Antibody, Clone S355-1 - SMC-440

BHA11904267
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+1 866.986.9598
Email
[email protected]
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Swissprot P19490
Accession Number NP_113796
Gene Id 50592
Target GluR1
Clone No S355-1
Research Area Neurotransmitter Receptors, AMPA Receptors, Cell Signaling, Glutamate Receptors, Neuroscience
Buffer PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~100kDa. Does not cross-react with GluR2.
Storage -20ºC
Storage Buffer PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB, ICC/IF
Description WB ; IHC ; ICC ; IF
Dilution WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Potier M.C., Spillantini M.G., Carter N.P. (1992) DNA Seq. 2(4): 211-218.

2. Puckett, C., et al. (1991) Proc. Nat. Acad. Sci. USA 88(17): 7557-7561.

3. Gregor, P., et al. (1993) Proc. Nat. Acad. Sci. USA 90: 3053-3057.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11904267-1 SMC-440D Unconjugated 100 ug $330
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BHA11904267-2 SMC-440D-A390 ATTO 390 100 ug $384
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BHA11904267-3 SMC-440D-A488 ATTO 488 100 ug $383
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BHA11904267-4 SMC-440D-A594 ATTO 594 100 ug $383
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BHA11904267-5 SMC-440D-ALP Alkaline Phosphatase 100 ug $376
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BHA11904267-6 SMC-440D-APC APC 100 ug $382
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BHA11904267-7 SMC-440D-BI Biotin 100 ug $378
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BHA11904267-8 SMC-440D-FITC FITC 100 ug $374
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BHA11904267-9 SMC-440D-HRP HRP 100 ug $370
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BHA11904267-10 SMC-440D-PCP PerCP 100 ug $382
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BHA11904267-11 SMC-440D-RPE RPE 100 ug $380
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BHA11904267-12 SMC-440S Unconjugated 12 ug $44
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