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Home / Primary Antibodies

GLRB Antibody

SKU : BHA10558422

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA088748
Alternative Names	Glycine receptor subunit beta; Glycine receptor 58 kDa subunit;
Categories	Primary Antibodies
Clonality	polyclonal
Description	The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).Handford C.A., Brain Res. Mol. Brain Res. 35:211-219(1996).Milani N., Genomics 50:341-345(1998).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GLRB.
Involvement In Disease	Hyperekplexia 2 (HKPX2)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Handford C.A., Brain Res. Mol. Brain Res. 35:211-219(1996). Milani N., Genomics 50:341-345(1998). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GLRB protein.
Subcellular Location	Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell junction, synapse, Cell projection, dendrite, Cell membrane, Multi-pass membrane protein, Cytoplasm

Uniprot	P48167
Database Links	HGNC:4329 OMIM:138492 KEGG:hsa:2743 STRING:9606.ENSP00000264428 UniGene:Hs.32973
Function	Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine
Protein Families	Ligand-gated ion channel (TC 1.A.9) family, Glycine receptor (TC 1.A.9.3) subfamily, GLRB sub-subfamily

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558422	CSB-PA088748	100ul	$297		Add to Cart

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