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Home / Antibodies

GGH Antibody

SKU : BHA10558415

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA789575
Alternative Names	conjugase; EC 3.4.19.9; folylpolygammaglutamyl hydrolase; gamma-Glu-X carboxypeptidase; gamma-glutamyl hydrolase
Categories	Primary Antibodies
Clonality	polyclonal
Description	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996).Yin D., Gene 238:463-470(1999).Basrur V., J. Proteome Res. 2:69-79(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GGH.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996). Yin D., Gene 238:463-470(1999). Basrur V., J. Proteome Res. 2:69-79(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GGH protein.
Subcellular Location	Secreted, extracellular space, Lysosome, Melanosome

Uniprot	Q92820
Database Links	HGNC:4248 OMIM:601509 KEGG:hsa:8836 STRING:9606.ENSP00000260118 UniGene:Hs.78619
Function	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Protein Families	Peptidase C26 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558415	CSB-PA789575	100ul	$297		Add to Cart

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