GFAP encodes glial fibrillary acidic protein, one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in GFAP cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Clonality
Monoclonal
Description
Mouse Anti-GFAP Monoclonal Antibody
Formulation
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host
Mouse
Immunogen
Synthetic Peptide
Immunogen Region
Synthetic Peptide
Isotype
Mouse IgG1
Molecular Weight
45 KD
Others
The antibody detects endogenous GFAP proteins.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity
Mouse, Rat
Tag
Glial fibrillary acidic protein
Note
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:2000-1:5000), IF (1:100-1:200), IHC-P (1:50-1:300).
Accession Number
P14136
Gene Id
2670, 2670
Concentration
1 mg/ml, 1 mg/ml
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer
PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.