GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9/4262 can be used in assays to detect GDF9 expression and help diagnose ovarian disorders.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Rat
Immunogen Region
Amino acids KKPLGPASFNLSEYFC from the N-Terminal region of the human protein were used as the immunogen for the GDF9 antibody.
Isotype
Rat IgG1
Species Reactivity
Human
Note
Optimal dilution of the GDF9 antibody should be determined by the researcher.
Uniprot
O60383
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the GDF9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Applications
ELISA, WB
Description
ELISA: order Ab without BSA for coating,Weste blot: 1-2ug/ml