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Home / Antibodies

GBP1 Antibody

SKU : BHA10559406

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA695454
Alternative Names	GBP-1; Guanine nucleotide-binding protein 1; Interferon-gamma inducible protein MAG-1; Interferon-induced guanylate-binding protein 1; MAG-1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.Cheng Y.-S.E., Mol. Cell. Biol. 11:4717-4725(1991).The MGC Project Team; Genome Res. 14:2121-2127(2004).Nantais D.E., J. Leukoc. Biol. 60:423-431(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GBP1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. Cheng Y.-S.E., Mol. Cell. Biol. 11:4717-4725(1991). The MGC Project Team; Genome Res. 14:2121-2127(2004). Nantais D.E., J. Leukoc. Biol. 60:423-431(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GBP1 protein.
Subcellular Location	Cytoplasm, Golgi apparatus membrane, Lipid-anchor, Cytoplasmic side, Cell membrane, Secreted

Uniprot	P32455
Database Links	HGNC:4182 OMIM:600411 KEGG:hsa:2633 STRING:9606.ENSP00000359504 UniGene:Hs.62661
Function	Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Pathway	NOD-like receptor signaling pathway
Protein Families	TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559406	CSB-PA695454	100ul	$297		Add to Cart

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