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Home / Primary Antibodies

GATA4 Antibody

SKU : BHA10557854

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA546814
Alternative Names	DNA binding protein GATA-GT2; GAT4; GATA binding factor-4; GATA-4; Transcription factor GATA-4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.Huang W.Y., Gene 155:219-223(1995).Garg V., Nature 424:443-447(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human GATA4.
Involvement In Disease	Atrial septal defect 2 (ASD2); Ventricular septal defect 1 (VSD1); Tetralogy of Fallot (TOF); Atrioventricular septal defect 4 (AVSD4); Testicular anomalies with or without congenital heart disease (TACHD)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. Huang W.Y., Gene 155:219-223(1995). Garg V., Nature 424:443-447(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total GATA4 protein.
Subcellular Location	Nucleus

Uniprot	P43694
Database Links	HGNC:4173 OMIM:187500 KEGG:hsa:2626 STRING:9606.ENSP00000334458 UniGene:Hs.243987
Function	Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function
Pathway	Cellular senescence cGMP-PKG signaling pathway

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557854	CSB-PA546814	100ul	$297		Add to Cart

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