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Home / Antibodies

GATA4 Antibody

SKU : BHA10557556

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA084937
Alternative Names	MGC126629
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5Garg V., Kathiriya I.S., Barnes R., Schluterman M.K., King I.N., Butler C.A., Rothrock C.R., Eapen R.S., Hirayama-Yamada K., Joo K., Matsuoka R., Nature 424:443-447(2003) Hirayama-Yamada K., Kamisago M., Akimoto K., Aotsuka H., Nakamura Y., Tomita H., Furutani M.,Matsuoka R.Am. J. Med. Genet. A 135:47-52(2005)
Host	Rabbit
Immunogen	Peptide sequence around aa.434~438(D-S-H-G-D) derived from Human GATA-4.
Involvement In Disease	Atrial septal defect 2 (ASD2); Ventricular septal defect 1 (VSD1); Tetralogy of Fallot (TOF); Atrioventricular septal defect 4 (AVSD4); Testicular anomalies with or without congenital heart disease (TACHD)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 Garg V., Kathiriya I.S., Barnes R., Schluterman M.K., King I.N., Butler C.A., Rothrock C.R., Eapen R.S., Hirayama-Yamada K., Joo K., Matsuoka R., Nature 424:443-447(2003) Hirayama-Yamada K., Kamisago M., Akimoto K., Aotsuka H., Nakamura Y., Tomita H., Furutani M.,Matsuoka R.Am. J. Med. Genet. A 135:47-52(2005)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total GATA-4 protein.
Subcellular Location	Nucleus

Uniprot	P43694
Database Links	HGNC:4173 OMIM:187500 KEGG:hsa:2626 STRING:9606.ENSP00000334458 UniGene:Hs.243987
Function	Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function
Pathway	Cellular senescence cGMP-PKG signaling pathway

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557556	CSB-PA084937	100ul	$297		Add to Cart

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